3-MeO-PCP

Buy 3-MeO-PCP for Research Toronto

Welcome to the premier destination for researchers in Toronto and across Canada looking to buy 3-MeO-PCP for research Toronto. We understand the critical need for high-quality research chemicals and are dedicated to supporting your scientific endeavors. This page provides a comprehensive overview of 3-MeO-PCP (3-Methoxyphencyclidine), a valuable compound for advanced pharmacological and neurochemical studies.

What is 3-MeO-PCP?

3-Methoxyphencyclidine, commonly known as 3-MeO-PCP, is a synthetic dissociative compound belonging to the arylcyclohexylamine class . It is a structural analog of phencyclidine (PCP) and was first synthesized in 1979 to explore the structure-activity relationships of PCP derivatives . As a research chemical, it serves as a crucial tool for studying the glutamate system, particularly the NMDA receptor, which is a primary target for its action .

Key Features and Properties

• Chemical Name: 1-[1-(3-Methoxyphenyl)cyclohexyl]piperidine 

• CAS Numbers:

  • Free Base: 72242-03-6 

  • Hydrochloride (HCl): 91164-58-8 

• Molecular Formula: C₁₈H₂₇NO 

• Molecular Weight: 273.41 g/mol 

• Appearance: White to off-white crystalline powder 

• Purity: ≥98% (as confirmed by GC-MS, HPLC, and NMR analysis) 

Pharmacological Profile and Research Applications

3-MeO-PCP is distinguished by its high affinity for the NMDA receptor, where it acts as a potent antagonist . Its binding affinity (Ki) is approximately 20-38 nM, which is higher than that of PCP itself, making it a potent tool for researchers . In addition to NMDA receptor antagonism, 3-MeO-PCP also shows significant affinity for the sigma-1 (σ₁) receptor and the serotonin transporter (SERT) . This multi-target profile makes it valuable for various fields of study:

• Neurochemical Research: Investigating the role of the NMDA receptor complex and its interaction with other neurotransmitter systems like dopamine and serotonin .

• Receptor Binding Studies: Characterizing the binding properties and functional effects of arylcyclohexylamines at different receptor sites .

• Structure-Activity Relationship (SAR) Studies: Exploring how structural modifications, such as the methoxy substitution at the 3-position, affect receptor affinity and pharmacological activity .

• Behavioral and Neuropharmacology Models: Studying the effects of dissociative substances on cognition, pain processing, and sensory perception in preclinical models .

• Forensic and Analytical Toxicology: Serving as a reference standard for the detection and quantification of this compound in biological samples .

Product Specifications and Quality Assurance

Our 3-MeO-PCP is supplied as a high-purity crystalline powder, ideal for research applications. Each order is accompanied by a comprehensive Certificate of Analysis (COA) and Safety Data Sheet (SDS) to ensure transparency and quality control . It is recommended to store the product in a cool, dry place, preferably at -20°C for long-term stability, and to handle it under a fume hood using appropriate laboratory safety protocols .

When you decide to buy 3-MeO-PCP for research Toronto, you can trust that you are receiving a product that meets rigorous research standards. Our commitment to quality ensures that your experiments are based on reliable and consistent materials. We encourage you to explore our full catalog to see how we can support your next research project. Our efficient shipping network ensures that your order arrives securely and on time, wherever you are in Canada.

Why Choose Us as Your Supplier?

• High-Purity Product: All our chemicals, including 3-MeO-PCP, are tested to ensure a purity of ≥98%.

• Comprehensive Documentation: We provide complete batch-specific analytical data, including COAs and SDSs.

• Secure and Discreet Shipping: We understand the importance of privacy and ensure all shipments are packaged with the utmost discretion.

• Research-Focused: We are dedicated solely to supplying the scientific community with the tools needed for groundbreaking research.

• Reliable Customer Support: Our team is available to assist with any inquiries regarding product specifications or your order.

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FAQ

1. What is the CAS number of 3-MeO-PCP?
The CAS number for the free base is 72242-03-6, and for the hydrochloride salt, it is 91164-58-8.

2. Is 3-MeO-PCP intended for human consumption?
No, 3-MeO-PCP is strictly for research and laboratory use only and is not approved for human or veterinary consumption.

3. What are the primary research applications of 3-MeO-PCP?
It is primarily used as a potent NMDA receptor antagonist in neuropharmacological research, receptor binding studies, and structure-activity relationship (SAR) analyses of arylcyclohexylamines.

4. How should I store 3-MeO-PCP?
It should be stored in a dry, cool place, ideally in a freezer at -20°C, to maintain its stability and shelf life.